TOPKERATO CREAM

TOPKERATO CREAM attracts and holds water, resulting in transepidermal water migration. High concentrations of urea dissolve proteins and used as a denaturant. Has a hydrating & keratolytic property. TOPKERATO CREAM attracts and holds water, resulting in transepidermal water migration. High concentrations of urea dissolve proteins and used as a denaturant. Has a hydrating & keratolytic property.

UREA is known to exert a Proteolytic, Keratolytic, Hydrating, Hygroscopic, Penetration-Enhancing, Epidermis-Thinning, and Antipruritic Effect.

Topical keratolytic agents are widely used in dermatology to debride scaling and as penetration enhancers of agents such as corticosteroids and antifungals. They work by dissolving intercellular matrix proteins and loosening the stratum corneum while simultaneously moisturizing the underlying epidermis

Clinical uses of TOPKERATO (topical 40% Urea Cream):

• Hyperkeratotic conditions: Dry, Rough Skin, Dermatitis, Psoriasis, Xerosis, Ichthyosis, Eczema, Keratosis Pilaris, Keratosis Palmaris, Keratoderma, Corns and Calluses, as well as Damaged, Ingrown and Devitalized Nails.
• Nail diseases (Onychomycosis, Nail Psoriasis, Onychogryphosis)
• Verruca Vulgaris, Corns or Callosities.